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Deviations from the normal assumption for continuous variables were investigated using histograms and the D'Agostino test for skewness and kurtosis.
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Analyses involving Ki-67 and AI as continuous variables were investigated using analysis of variance.
Analyses involving Ki-67 as a continuous variable were investigated using ANOVA.
Variables were investigated using Student's two-sample t test for continuous variables, and Pearson's chi-square test and Fisher's exact test for categorical variables.
Differences in clinical variables according to mutation status were investigated using Fisher's exact test for categorical variables and the Mann–Whitney U-test for continuous variables.
Differences between the SSc subsets were investigated, using χ test for categorical variables and t tests for continuous parameters.
Associations were investigated using univariate logistic regression when the dependent variable was dichotomous and Pearson correlation for continuous variables.
The association between mammography history and baseline characteristics was investigated using Student's t test and chi-square test for continuous and categorical variables respectively.
Pearson's chi-square test or Fisher's exact test for categorical variables and Mann-Whitney U test for continuous variables were used for bivariate inference methods.
Fisher's exact tests for categorical variables and ANOVA for continuous variables were used.
For all models continuous predictor variables were investigated for linearity with the outcome variable using five quintiles.
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CEO of Professional Science Editing for Scientists @ prosciediting.com