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Group differences for continuous variables were examined using Student unpaired t tests and ANOVA models.
Unadjusted differences for continuous variables were examined using Student's t test and for categorical variables using the χ test.
Differences in means for continuous variables were examined using analysis of variance (ANOVA) and the non-parametric equivalent (Kruskal-Wallis) tests across the four stages of severity.
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The distribution of continuous variables was examined using percentile plots.
The normality of continuous variables was examined using the Shapiro-Wilk's W-test.
Categorical and continuous variables were examined using standard univariate tests for comparison.
Associations between categorical and continuous variables were examined using χ 2 tests for linear trend and non-parametric tests.
Continuous variables were examined using 2-tailed paired or 2-sample t tests.
Continuous variables were examined using analysis of variance (ANOVA) models.
Differences in continuous variables were examined using t-statistics, while differences in categorical variables were examined using chi-square statistics.
Continuous variables were examined using student's t-test, and categorical variables were examined using the chi-square test.
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