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Comparisons between outcomes for continuous variables were conducted using Wilcoxon two sample T test, while the chi-square test was used for categorical variables.
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Bivariate comparisons of continuous variables were conducted using one-way ANOVA.
Univariate analyses of continuous variables were conducted using Wilcoxon's rank-sum test and Fisher's exact test for categorical variables.
Analyses for the continuous variables were conducted using stepwise linear regression in which the baseline value of each outcome variable was entered in Step 1.
Comparisons for categorical variables were conducted using test of proportions, while Student's t-test was used for continuous variables.
Statistical analysis for continuous variables was conducted by one-way ANOVA.
Tests for linear trend were conducted using the median value for each exposure category analysed as a continuous variable.
Tests for trend were conducted using the median value for each category of nutrient as a continuous variable.
Tests for trend were conducted using the median values for each quartile of each plasma biomarker as a continuous variable in the regression models.
Bivariate analyses were conducted using t tests for continuous variables and χ tests for categorical variables.
Statistical comparisons of socio-demographic variables between male and female patients were conducted using chi-squared tests and t-tests for categorical and continuous variables respectively.
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