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In order to sequence P. vivax directly from patient whole blood, 80 100 GB of raw sequencing data would be needed to achieve the desired depth for confident analysis.
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We did not differentiate between the different categories of p53 mutations (nonsense mutations, missense mutations, 'DNA-contact' mutations or 'conformational' mutations), as there were not enough cases in each p53 mutation category for confident statistical analysis.
This allows for confident quantification and analysis of the spatial localization, distribution and levels of the target proteins using quantitative 3D microscopy.
Proteomic technologies have significantly matured in the last few years, particularly for application in the clinical realm, where robust measurements can now be made with sufficient sensitivity and throughput to allow both the depth and breadth of analysis required for confident global comparisons of larger sample sets [ 33, 34].
We present topological analysis of co-abundance networks as an alternative to differential regulation for confident identification of target proteins from two related global proteomics studies of hepatitis C virus (HCV) infection.
Following a processing pipeline in which clinical trials were filtered for confident assignment of drug and placebo trial arms, 229 drugs with at least one human target were used in our analysis.
The terrain is ideal for confident intermediates.
The results of this study provide a foundation for developing the capability for confident quantitative sub-millimetre thermal imaging.
In glycopeptide analysis, the correct glycopeptide compositions usually cannot be determined by high resolution MS data alone, and MS/MS data are needed for confident glycopeptide assignments.
This correlation allows for confident rejection of incorrect structural models.
For this analysis, "confident", "quite aware", and "aware" were considered as positive answers concerning awareness.
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