Exact(29)
Therefore, the binding site prediction problem calls for computational methods.
Recent improvements in flexible docking technology may lead to a bigger role for computational methods in lead discovery.
For computational methods it is more difficult to study selectivity than activity because selectivity analysis requires the evaluation of compounds binding to multiple targets [2].
Therefore, applications of our framework will prove instrumental in gradually establishing the guidelines for computational methods of insurgency and continuing to meet them via innovative frameworks.
Recent technologies such as microarray and next-generation sequencing have paved the way for computational methods and techniques to play critical roles in this regard.
As the number of determined structures of membrane proteins increases so does the need for computational methods which predict their position in the lipid bilayer.
Similar(31)
This problem is especially clear when one attempts to account for the increasing use of computational methods for performing tasks that were traditionally accomplished by measuring instruments.
Because of the high cost of experimental identification of such peptides, there is an urgent need for reliable computational methods for predicting MHC binding peptides [1].
This module also is related to module 8 below for determining computational methods for locating CpG islands on the genome.
The rationale for developing computational methods for the prediction of secondary and tertiary structures of biopolymers emanates from the technical and cost limitations imposed by available biophysical methods.
Irrespective of what choice of method that is preferred, there is a definite need for better computational methods for quantification of interactions.
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