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Jesse Ausubel, director of the Census for Marine Life, financed by the Alfred P. Sloan Foundation, is among those environmentalists pushing for comprehensive mapping.
While whole-genome bisulfite sequencing is the gold standard for comprehensive mapping of methylation events, it is still expensive and requires a high level of specialization.
While viral-mediated expression could be used to estimate the divergence of inhibitory projections from a single stimulation site, it was not suitable for comprehensive mapping of convergence onto individual SNr neurons.
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Together with genomic binding data, ANRO will provide the heretofore missing transactome for the comprehensive mapping of any transcriptional network.
The decision taken was that there was in fact a need for a comprehensive mapping and scoping exercise.
While the current approach yielded several potential loci and candidate genes, additional inbred strains would provide increased power for more comprehensive mapping.
While current databases and information portals have accumulated a large amount of information on kinase SNPs, there is a growing need for integration and comprehensive mapping of diverse data categories on protein kinase genes within a central resource.
Here, we present X-MATE, a system for flexible and comprehensive mapping of all deep-sequencing datasets.
However, despite the implications of functional lateralisation theories for neurodevelopmental and psychiatric disorders6,7, as well as for stroke recovery8,9,10,11, a comprehensive mapping of functional lateralisation in the brain is, to our knowledge, still missing in the literature.
In the present study, we provide for the first time a comprehensive mapping of the functional brain architecture of lateralised cognitive functions.
Recent efforts combining genomic and ChIP-obtained data on human alpha-satDNA allowed the possibility for comprehensive functional mapping of centromeric areas and led to a model in which the centromere is defined by sequence features and context-dependent epigenetic interactions (Hayden et al. 2013).
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