In Fig. 2 this clade of AroQTyrAc_Δ fusions was presented as one exhibiting absolute specificity for NAD+, combined with an overwhelming but not complete specificity for PPA.
The PCR assays were evaluated in three different combinations of primer pairs in order to assure complete specificity for each reaction.
In the present study, we exploited these differences to develop an assay, measuring citrullination of fibrinogen, with almost complete specificity for PAD2 activity.
The analysis of different NTPs (ATP, UTP, GTP, dTTP) as substrates of ADP-Glc PPase and UDP-Glc PPase (assayed up to 5 mM) showed complete specificity for the use of ATP and UTP, respectively.
This collection contains a partial or complete specificities for a total of 325 fruit fly TFs.
For complete results of specificity testing see Table 2.> The LOD of each diagnostics assay was evaluated in both monoplex and multiplex real-time PCR formats.
Briefly, plots of sensitivity and (1-specificity) for complete pathologic tumour response were obtained for each marker and the (0,1 -criterion was used to select the threshold value, or protein expression score, above which expression was to be considered 'positive' (Bewick et al, 20,1 -criterion
For complete response: sensitivity = 46%, specificity = 86%, positive predictive value = 71%95%5% CI 45−88%), negative predictive value = 70%95%5% CI 53−82%), accuracy = 70%.
The aggregated performance characteristics of CT for complete obstruction were sensitivity of 92% (range, 81 100%), specificity of 93% (range, 68 100%), PPV of 91% (range, 84 100%), and NPV of 93% (range, 76 100%).
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