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The three main research components of his laboratory are focused on the themes of the basic neurobiology of cognition and addiction, neurobehavioral toxicology and the development of novel therapeutic treatments for cognitive dysfunction and substance abuse.
Lewis, D. A. Inhibitory neurons in human cortical circuits: substrate for cognitive dysfunction in schizophrenia.
Sleep-disordered breathing is known to be a risk factor for cognitive dysfunction in the general population, but this association has not been studied in patients with CKD.
The objective of this study was to characterize and determine risk factors for cognitive dysfunction in children, adolescents, and young adults with CKD compared with controls.
The interest for PDEs as targets continues to grow within therapies to treat CNS diseases, particularly for cognitive dysfunction and neuropsychiatric diseases.
Vascular pathology is a strong risk factor for cognitive dysfunction [5, 6].
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These observations, together with accumulated clinical findings, suggest that the NO system is a potential treatment target for cognitive dysfunctions in schizophrenia.
Our finding therefore of reduced GluN2B protein in the hippocampus, is likely to contribute to the cognitive symptoms in schizophrenia patients, and supports the idea that GluN2B positive allosteric modulators could potentially be therapeutic for cognitive dysfunctions in schizophrenia.
Although in the current paper we aimed to focus proving that EA owned the possibility for improving cognitive dysfunction, the specificity for EA treatment in AD model still need further exploration.
The implication is that "the surgery or the medical conditions surrounding surgery" are responsible for subsequent cognitive dysfunction, she noted.
Thus, it seems that the tendency to abuse cannabis with ecstasy may be for avoiding cognitive dysfunction.
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