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Nevertheless, the protein and gene name rule is still useful in removing false positive matches for certain protein names.
As to the idea that the benchmark of VS programs may help for creating a strategy to be used for certain protein families, it seems to us rather unrealistic.
Two protein kinase inhibitors, staurosporine and H-7, inhibited the activity of all three kinases in vitro, while a peptide inhibitor (PKC 19-31) specificityifority for protein kinase C. In summary, these results suggest that activation of messenger-independent protein kinases may be critical for certain protein kinase C-dependent responses.
On the other hand, Wang et al. [25] have reported from a comprehensive evaluation of ten docking programs that the correlation between the scores of some programs (Gold, Glide and Surflex, among others) and the binding affinities may be high for certain protein families (up to 0.7).
Its natural counterpart, purpura fulminans, occurs in children who are homozygous for certain protein C mutations.
Strictly speaking, an optimal solution to the protein structure alignment problem is only known for certain protein structure similarity measures, such as the measures used in protein structure prediction experiments, GDT_TS and MaxSub.
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Recent studies indicate that an addition of a small amount of energetic frustration may enhance folding speed for certain proteins.
While the proteosome can selectively target certain proteins that are supposed to live for a short period of time, autophagy is used to digest large organelles and long-lived proteins, and it cannot select for certain proteins.
Gene transcription is the process by which DNA (deoxyribonucleic acid) codes for certain proteins by producing specific molecules of messenger RNA (ribonucleic acid) that direct the synthesis of those proteins.
Herceptin only works in some breast cancer patients, but these candidates can be identified with a diagnostic test that looks for certain proteins in the tumor.
However, this characteristic has been exploited positively for certain proteins, (Gregory et al. [2013]) have successfully expressed the structurally complex non-glycosilated proteins Pfs25 and Pfs28 from Plasmodium falciparum, the parasite responsible of malaria.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com