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In addition to the number of fulfilled ACR-82 criteria, significant differences between the ACR-82 and Fries groups were found for certain manifestations related to skin, renal, neurologic, hematologic and immunologic items.
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The recognition of the strong association of certain manifestations with the complex and the specific constellation of symptoms that these patients experience is important for establishing the appropriate diagnosis and treatment.
This function expresses the probability for a certain manifestation of the random variable X.
Whether this reflected a selection bias for certain clinical manifestations is not known and overestimation of the seropositivity rate in some of the clinical subgroups is possible.
The detection of autoantibodies, especially directed towards topoisomerase I (anti-topo I), can help to identify patients at risk for progressive and severe disease and to classify them according to their disposition for certain clinical manifestations [ 1- 6].
In summary, our findings as well as those reported previously [ 17- 20] suggest that some serotypes have a propensity to invade one clinical site rather than another and may therefore be disproportionately responsible for certain disease manifestations.
Cohort studies do have significant strengths: they can be used to study high-risk patients even before they develop certain manifestations; several outcomes can be studied for each exposure; and statistical modelling can be applied to determine significance in-depth.
This allows for use of DBSS samples in a retrospective study of 22q11.2 deletion among certain manifestations associated with DiGeorge Syndrome.
The chakragati (ckr) mouse is beginning to provide valuable insights into the structural brain changes underlying certain manifestations of schizophrenia.
Although more women than men have died of cardiovascular disease since 1984, men appear to be particularly susceptible to certain manifestations of the disease.
She can still castigate cruelty, but she appears willing both to smile a little and to weep a bit at certain manifestations of human foolishness.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com