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In both cases, the site of improvement was spatially separated from the region of antibody mediating molecular contact with the protein component of the antigen, thereby improving peripheral semi-specific interactions while maintaining unmodified dominant contacts responsible for broad recognition.
Although multivalency plays a role in increasing avidity of interactions of many glycan-binding receptors, for the mannose-binding protein the geometry of the placement of multiple binding sites facing a single direction is a determining feature for broad recognition of glycan-rich surfaces without requiring specific complex oligosaccharide structures (Weis and Drickamer 1994).
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Sir Elton John released a statement calling for broader recognition for the singer.
Newcastle's little-known, but hugely valuable, photography collective is making a bid for broader recognition.
In a further bid for broader recognition, Mr. Zander has begun to record Beethoven and Mahler symphonies with the Philharmonia Orchestra of London for Telarc.
Mostly college bound and unfettered by the worldly concerns that usually occupy musicians struggling to make it, they are free to indulge their whims, an impulse that eclipses the desire for broader recognition.
The Universal Declaration of Human Rights and the collapses of colonialism, Fascism, and Communism paved the way for broader recognition of individual freedoms previously denied, rejecting what had amounted to imposed statuses of perpetual non-innocence.
To advocates of the disabled, Wemedia's sports strategy fills a long-overlooked void and will provide broad recognition for their athleticism.
NK and iNKT cell receptors provide broad recognition for the innate response via a limited repertoire of activating and inhibitory NK cell receptors (for NK cells) [ 1] or a semi-invariant NK T-cell receptor (TCR) (for iNKT cells) [ 2], while CTLs provide the highly specific recognition of the adaptive response by use of many different TCRs.
She is one of Germany's most beloved politicians, enjoying high personal approval ratings and broad recognition domestically for her handling of the euro crisis.
For the first time, there is a broad recognition that the issues the SDGs seek to address are not defined by borders or governments.
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CEO of Professional Science Editing for Scientists @ prosciediting.com