Pharmacophore models are typically derived from structural features common to biologically active ligands that are hypothesized to be important for biological activity [1 5].
Latent TGF-β cannot bind TGF-β receptors and thus further activation processes are required for biological activity [12].
Both landers had mechanical arms, to gather soil samples, and built-in labs to check for biological activity.
Seasonal changes in the planet's appearance, attributed to the spread and retreat of vegetation, added further to the purported evidence for biological activity.
A total of 226 screens tested hitachimycin for biological activity.
Phosphate is frequently a limiting nutrient for biological activity in natural terrestrial subsurface systems [13].
Graphical abstract Conformations of PheB25 and PheD25 in three insulin structures: implications for biological activity?
Experimental screening of chemical compounds for biological activity is a time consuming and expensive practice.
At R2 position, less bulky group would be favorable for biological activity, indicated by yellow polyhedral.
Additionally, it represents an activity threshold that is more relevant for biological activity.
Klekota-Roth fingerprints (set of 4860 chemical substructures enriched for biological activity [17]), 7.
