Sentence examples for for binding to this from inspiring English sources

Increased NADP+ activates G6PD by competing with NADPH for binding to this enzyme.

We therefore initiated a 3D-QSAR study to develop predictive models for compound binding and identify structural features important for binding to this transporter.

Furthermore, we found that NADP+, which is known to activate G6PD by competing with NADPH for binding to this enzyme, plays a role in stabilizing G6PD dimers by blocking the p53-G6PD interaction (Jiang et al., 2011).

At cell surface, both HFE and diferric-iron-loaded transferrin (Fe2-Tf) recognize overlapping regions on TfR1, which results in competition for binding to this receptor [10].

As noted above, there is no evidence in our structures for binding to this second site.

Interestingly, SN34452 largely retains its potency against PI4K TypeIIIβ (Table 2), which indicates the carboxamide is not critical for binding to this enzyme.

It is possible that WT α2δ-1 and PrP interact indirectly via an intermediary trafficking protein and compete for binding to that protein, whereas this does not occur when one of them is not membrane-anchored.

This might reflect the need for binding to the PACS sorting adaptor via this motif in order to target the receptors to this compartment.

Moreover, it has been shown that minus and plus end motors compete for binding to the same region of this protein complex and that impairment of the dynactin complex abolishes both plus and minus end motion of several bidirectional cargoes [27], [28].

The absolute values of KDs obtained for binding to the individual ligands obtained by this method are around an order of magnitude lower (tighter binding) than those obtained for the same ligands in solution by ITC.

A limitation of this method, however, is that sulfonic acid-modified peptides are in competition with phosphorylated peptides for binding to the PA-coated nanodiamonds, though this could potentially be reduced by phosphatase treatment of lysates.