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For better specificity, however, we need to redirect drugs from the pleiotropic calmodulin target to docking site at the pore loop of TRPV1 (Figs. 10 and 11).
Should we instead be looking for better specificity?
The authors proposed that the superior spatial resolution and resultant anatomical localisation with NaF-PET was responsible for better specificity and no quantitative comparison was made.
The modified receiver operating characteristic curve in Figure 2 shows that variation of the threshold for weighted trends may reduce sensitivity for better specificity (less FP alarms per patient-year of monitoring).
Stem-loop reverse transcription PCR (RT-PCR), which can be applied in small RNA cloning and multiple assays for better specificity and efficiency, was used for reverse transcription [ 86].
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The temperature of annealing was higher for following cycles because of better specificity of the PCR reaction.
It was suggested that the L-shaped quinone substrates for NQO1 possessed better specificity and safety than β-lapachone.
SPR results show better specificity for that sequence with DB1255 than for the DB293 dimer (Table 1).
Expectations were raised that visualization and quantification of apoptosis, as a more specific and relevant marker of cell death, may provide better specificity for assessing actual tumour cell elimination following treatment.
Taken together, TTF-1 had a better sensitivity, and Napsin A had a better specificity for the primary lung ADCs.
In contrast, AFP-L3, consisting of core-fucosylated glycoforms of AFP, provides better specificity for HCC[ 14].
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