Exact(1)
These include the need for better dosing strategies; the frailty of cancer patients who are much sicker than tumor-bearing mice and therefore cannot withstand the toxicities associated with high dose therapy; and "vascular normalization", a period of time following anti-VEGF/VEGFR therapy in which tumor vessels normalize structurally and lose their hyperpermeability.
Similar(59)
The need for late data points for better dose estimation for 177Lu-octreotate is also shown.
Material specific absorption parameters allow for better dose estimation than using ICRP default values for F (fast), M (moderate) and S (slow) classifications of U compounds.
Hence, a wider overlapped region is preferred for better dose uniformity.
These measurements will enable better dosing and scheduling for the emerging next generation of compounds.
This would also reduce the time required for treatment and give a better dose distribution.
Innovative technologies that allow for real-time imaging and better dose distribution have significantly improved the therapeutic ratio of radiotherapy.
In the postgenome era, a prediction of response to treatment could lead to better dose selection for patients in radiotherapy.
For the majority of patients; equally spaced, coplanar three-dimensional chemoradiation (3D-CRT) field plans (box-field) were generated; however, intensity-modulated radiation therapy (IMRT) was also generated for some cases, to achieve better dose distribution.
It advises cocaine users to finely chop their powder "for better interaction with the nasal lining, better dose management, easier snorting action reduced waste and nasal damage".
Twelve rules for dose calculation of chemotherapy are given that can be used as a guideline until better dose-calculation methods become available.
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