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The researchers screened a library of just over 300 oximes for their ability to bind to a cell-signaling protein called Src, which is thought to be overly active in cancer and osteoporosis.
A gene that is overly active could cause increased secretions of a protein that may serve as a marker for a cancer.
"A lot of people who've done a lot of drugs, or drink too much, or have a sexual life that is overly active or not active enough.
In cancers that have normal p53, sometimes HDM2 is overly active and prevents p53 from suppressing tumor formation and growth.
Some attacked me for being overly academic.
"I'm known for being overly communicative.
"People criticize New York for being overly liberal," he said.
First, the sciences are criticized for being overly specialized.
Women are criticized for being overly cooperative and caring doormats.
It has drawn criticism for being overly broad.
The Fund's grant rating methodology was criticized for being overly numerical.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com