Sentence examples for for an imputation from inspiring English sources

This stresses the need for an imputation method that can impute genotypes that have not been observed in the sample.

Above, we referred to the weighted scheme to motivate why we looked for an imputation bias, but it should be pointed out that the result, that bias exists, is more general.

In total, we simulated a region of 1,050 kb, including a 50 kb gene and 500 kb up- and down-stream to allow for an imputation buffer to improve accuracy by avoiding edge effects and taking advantage of the expected long-range linkage disequilibrium (LD) with rare variants [ The International HapMap Consortium, 2007.

Even if the imputation methodology is chosen because of the user's concerns, the suite of validation statistics have empirically demonstrated their ability to indicate out the adequacy of an imputation technique for a specific problem.

In a standard GWAS (of genotyped SNPs only), the presence of a number of SNPs in the same region showing the same signal is generally considered an indication that the signal is reliable; however, the same can clearly not be said for an imputation-based GWAS.

For multivariate, non-monotone missing data there are two main approaches for constructing an imputation model: joint modelling and chained equations.

Besides allowing for a high imputation accuracy, imputation approaches based on pre-phasing are computationally efficient.

For many studies, an imputation method with less bias in allele frequency estimation, such as LD-kNNi, may therefore be preferable to a method with slightly increased accuracy.

MVs were imputed by using the MICE (Multivariate Imputation by Chained Equations) algorithm and R package [ 18], which allows for building up an imputation model with mixed-type covariates.

Missing data will be dealt with by the Multiple Imputation method, which is suitable for ANOVA and uses an imputation method with error built in.

We presented an imputation technique for dealing with missing values that arise in PPI prediction tasks.