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These observations have driven a search for alternative interventions, including isolated tension band wire fixation [14], minimally invasive plate osteosynthesis (MIPO) [2], and hybrid external fixation [15].
In choosing among these and other policy alternatives, please bear in mind the message presented above: that policy decisions should be based on comparisons of social benefits and social costs for alternative interventions.
Furthermore, the literature on the small number of participants who do not benefit from HF, a target population for alternative interventions and supports, is scant.
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These findings have important implications for alternative intervention strategies.
A better understanding of the mechanisms acting at the maternal-fetal interface is crucial for the design of alternative interventions to antiretroviral therapy for transmission prevention.
Additionally, there is a paucity of evidence among child populations and for the comparative effectiveness of alternative interventions.
Various models of decision making in health care stress the importance of incorporating patients' values for the possible consequences of alternative interventions into a decision [14], [15].
1. Study design: economic evaluation since the aim was to compare costs and outcomes of alternative interventions competing for the same resources 2. Study interventions: drug therapies or vaccines only since these are the ones listed on treatment guidelines and national essential medicine list 3. Study setting: Tanzania 4. Publication type: Original full articles or reports 1.
Furthermore, this and other studies indicate that the availability of alternative interventions is essential for effective restraint reduction [ 19, 23- 25].
In evaluative health care research, the randomized controlled trial is generally considered the gold standard design for assessing the relative effectiveness of alternative interventions, as it ensures that selection bias and other common sources of bias are minimized [ 1].
QALYs are then used as the unit of assessment for comparing the cost-effectiveness of alternative interventions [ 15] and are now used to inform resource allocation decisions worldwide [ 16].
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CEO of Professional Science Editing for Scientists @ prosciediting.com