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It was implemented using the scikit-learn [40] Python libraries for all ML processes.
The Mkv model of Lewis [89], using the default search strategy of Mesquite, was chosen for all ML ancestral state reconstructions.
A successive approximations approach was used for all ML analyses [ 19, 64].
We used the GTR + Γ + I model for all ML analyses of the nucleotide datasets.
The model of sequence evolution used was the same for all ML analyses.
For all ML analyses we also calculated a NJ tree using distances calculated from the ML model being tested.
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In the LMs, the number of infiltrating DCs was not significantly influenced by ML-I treatment (P>0.05, for all ML-I doses; Figure 4B).
It was mandatory for all MLs to undertake a needs assessment exercise.
The median (interquartile range; range) volume of blood taken for culture for all the children was 2.0 mL (1.6 2.5 mL; 0.1 13.2 mL).
Support for this subclade was strong for all proteins (ML bootstraps were 100, 98, 100, 92, 92 for P (module 2), C, G, I and M, respectively) except for J (see below).
We considered eight rate categories for the γ distribution in all ML analyses.
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