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For all alignment procedures we used PAM120 and Blosum62 as substitution matrices with uniform costs for gap opening and gap extension.
We used default parameters for all alignment estimates.
The sequences were analyzed for mis-assemblies and manually checked for all alignment conditions.
It is well known that repeats cause serious problems for all alignment algorithms [ 12].
This trend in performance is supported by Figure 3, which displays examples of CVE curves for all alignment methods tested.
For BAM, the index remains around 6 MB for all alignment sizes while Tabix index is three times smaller.
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For all the alignment of interests and calculation of the larger political currents, some Uzbeks said the feeling of support was remarkable, given the physical and psychological distance between the two nations.
For all these alignment programs considerable user-designed secondary processing is necessary to arrive at a list of reliable SNPs and their properties.
If at least two shared GO terms are used to determine FC, HubAlign greatly outperforms GHOST for all the alignments.
Specifically, we used the local gapped alignment algorithm for all alignments, keeping the default parameters for mismatch and deletion costs.
In the absence of splice-version specific sequence data of 3'UTRs in GBMs we accounted for all alignments of miRs and un-translated regions of a given mRNA.
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