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In fact, only one agent, lurasidone, has been approved by the FDA for adjunctive use (combined with lithium or valproate) for bipolar I depression (Latuda [package insert], 2013).
They were continued because Sativex was proposed for adjunctive use in painful DPN.
Despite being approved for adjunctive use in the treatment of major depressive disorder [ 24], aripiprazole was no more effective than placebo in alleviating depressive symptoms at endpoint in patients with bipolar I disorder [ 25].
It should be considered in patients with major abdominal injury and a need for adjunctive use of angioembolisation, major abdominal injury and a need to evaluate early on other possible injuries, major abdominal injury and traumatic amputation of a limb.
92 Liraglutide has also been approved in the European Union for adjunctive use in patients with type 2 diabetes and inadequate glycemic control with MET, SFU, MET and SFU, or MET and TZD combination therapy.
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Unfortunately, to date, evidence-based support for the adjunctive use of skin care products in oncology therapy remains scarce.
10, 28 CHOICE is a prospective, multinational, noninterventional observational study that recruited patients from six European countries (Denmark, Belgium, France, Germany, Greece, and Sweden) between January 2008 and October 2009 (prior to the expanded label for exenatide BID to include adjunctive use with a thiazolidinedione or basal insulin).
Endovascular treatment for aortic arch aneurysms often requires adjunctive use of hybrid debranching procedures to maintain branch vessel perfusion.
Adjunctive use of LBC for the index cervical cytology was by far the strongest predictor of LBC use in a subsequent cervical cytology test; when LBC was used in the index cytology, the odds of using LBC in the subsequent test were increased by more than 13 times, even after adjusting for all other factors (OR 13.6, 95% CI 13.3-13.8).
However, a randomized study showed that adjunctive use of intravenous dexamethasone for postpartum patients with severe preeclampsia did not reduce disease severity or duration [ 147].
For severe cases of endophthalmitis or vitritis, the adjunctive use of vitrectomy is recommended [73].
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