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Texture analysis can demonstrate equivalent changes in patients with metastases but with the benefit of utilising routinely acquired images, thereby avoiding the need for additional scanning[ 35 ],[ 36 ].
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Especially for a candidate mAb with a potential future as ADC, the resulting information (prevention of potential toxicity/additional development costs) may justify the patient burden and cost for additional scans in a limited number of patients in a phase I setting.
Expectant parents' desire for additional scans was commonly mentioned and the obstetricians sometimes commented on the disappointment expressed by women if they were not offered scans during visits.
This obviates the need for an additional scan with another contrast bolus, saving radiation and contrast dose Open image in new window Fig. 4 Low-contrast dose study.
Reassurance that everything was fine was described as the main expectation of the examination by expectant parents, and also the incentive for wanting additional scans.
For lag periods of five and 10 years, the IRR increased by 0.13 (0.10 to 0.16) and 0.10 (0.06 to 0.15), respectively, for each additional scan (web fig A). *Exposure status at end of study.
Consequently, use of this method would require an additional scanning session for each subject.
The entire MRI examination of the lungs can be completed in less than 10 minutes, even if additional scanning is performed for suspicious nodules.
In addition, some women will be called back repeatedly for additional procedures, scans and biopsies that ultimately rule out cancer but can be painful and anxiety-provoking.
This prospective study was conducted with patients referred for FDG PET/CT who gave written informed consent for additional MRI scans during the FDG uptake time.
This not only avoids the need for additional database scans, but also enables the use of existing PSP mining algorithms to mine for NSP.
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CEO of Professional Science Editing for Scientists @ prosciediting.com