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In order to search for additional instances, we analysed published GWAS http://www.genome.gov/26525384 and, in addition to the aforementioned variant in PTPN22, we identified rs744166 in STAT3 and rs2201841 in IL23R (Table 1).
But she is the one who has been left to clean up the mess and respond to authorities now combing through appropriation after appropriation, looking for additional instances where council members inappropriately steered money to favored community groups.
To find the full set of problematic structures, the entire database should then be searched for additional instances (e.g. all those structures with a 180° bond angle as shown in Figure 5).
We focused our attention on the intermolecular cross-links that were identified twice or more, for which the probability of being observed by random chance was below 10−8 for at least one instance and below 10−3 for additional instances (a false discovery rate cutoff of 0.05, an E-value cutoff rate of 10−3, spectral count ≥2, and the best E-value cutoff of 10−8).
Highly sensitive detection methods [25] now make it possible to follow the sequencing of cases and controls by probing for additional instances of the newly detected variants in a very large number of individuals through the use of a feasible number of pooled samples.
To separate the SNAREs and energize them for additional instances of trans-complex assembly and membrane fusion, Sec17 binds the cis-SNARE complex, in turn recruiting Sec18.
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The fines Weinstein would have paid the company ― "$250,000 for the first such instance, $500,000 for the second such instance, $750,000 for the third such instance, and $1,000,000 for each additional instance," according to TMZ ― are larger than the settlements he paid his accusers. .
There are, however, additional instances, for example, icons include diagrams used in geometrical reasoning, indices include pointing fingers and proper names, and symbols including broad speech acts like assertion and judgment, all of which suggests a considerable broadening of this trichotomy.
This extra latency can be found in Figure 9A, where the filtered result in red of Twice Half-Window Gaussian filter is pushed toward right for additional 2 time instances compared with the filtered result in blue of Half-Window filter (Figure 11A).
We reasoned that living in a region with a higher smoking rate might be a surrogate for additional risk since higher instances of regional smoking might lead individuals to maintain or intensify smoking behavior 12 as well as to a higher exposure to the damaging byproducts of smoking 13.
Our model can be extended to allow for additional protein flexibility, for instance, by sampling different conformations of the protein, similar to Ben-Tal et al. (51), and for each conformation minimize the free energy further with our dynamic scheme.
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CEO of Professional Science Editing for Scientists @ prosciediting.com