Sentence examples for for achieving efficacy from inspiring English sources

Results: The trial was stopped after the planned interim analysis for achieving efficacy endpoints and owing to safety concerns.

Unless we consider a so-called pro-drug, which requires metabolic activation for achieving efficacy, an otherwise unstable compound usually undergoes attrition during the drug development.

Achieving efficacies in the region of 90% for any one intervention in Liberia would be challenging, if not unrealistic.

The CAMHB MIC data satisfied integrated PK/PD relationships predicted to achieve efficacy for approximately 48 h after dosing; mean values for serum were 5.13 (Cmax/MIC), 49.3 h (T > MIC) and 126.6 h (AUC96h/MIC).

Recursively triggering hyperactive CARs rendered CTLs highly susceptible to activation-induced cell death resulting from augmented FasL expression, indicating that activation-induced cell death may be a critical parameter for achieving clinical efficacy against solid tumors.

Ritonavir administered at a low dose to boost another protease inhibitor may be a useful strategy for achieving virological efficacy while minimizing the toxicities associated with full-dose ritonavir.

We also propose that the design of CRAds should consider stromal cells as a potential target for achieving improved efficacy.

Further research is needed to identify the optimal LLLT parameters for achieving therapeutic efficacy, particularly for functional outcomes, and for understanding its mechanisms of action.

Nevertheless, a major challenge faced in the clinical application of MSC is the need for adequate cell numbers for achieving optimal efficacy in transplantation therapy.

Antibodies that achieve efficacy wholly or predominantly through Fc-mediated mechanisms, represent rich opportunities for future therapeutics in oncology.

The rationale for this design is based on clinical findings indicating that BCG therapy requires multiple dosing to achieve efficacy.