Sentence examples for for abnormal expression from inspiring English sources

We examined a series of 38 pediatric osteosarcomas for abnormal expression of pRB, p16 INK4a) and cyclin D1 by immunohistochemical analysis of archival biopsy specimens.

DESIGN: We examined a series of 20 pediatric EFTs for abnormal expression of p16 INK4a), p14 ARF), p21 WAF1), and pRB by immunohistochemical analysis of pretreatment, nondecalcified archival specimens.

First, we examined for abnormal expression of FGFR3 and FGFR4 in clinical prostate cancer specimens.

To determine the cutoffs for abnormal expression of individual protein, we first analyzed the distribution of the composite scores for abnormal expression of β-catenin, cyclin D1, EGFR, E-cadherin, and c-MET proteins between the normal and tumor tissues.

The cutoff values for abnormal expression were determined as follows: MDM2 > 30% [ 25]; p53 > 5% [ 26]; p16 < 5% [ 9].

Thus, the results presented here highlight a potential value for evaluating coding variants that affect ESE/ESS for abnormal expression even if they do not influence splicing.

Immunohistochemical staining showed that the frequency of abnormal expression was 24.3% for ATM, 32.1% for BRCA1 and 28.4% for TP53, and that high-grade tumours tend to have an increased frequency of abnormal expression of these three proteins.

When the frequency of abnormal expression of individual proteins was correlated with tumour grade using the Mantel-extension χ test for trends, there was a significant trend to an increase in abnormal BRCA1 expression with higher grade (P=0.036).

Hydrogen peroxide (H2O2), a member of reactive oxygen species (ROS), usually acts as a significant oxidative stress marker in some diseases for its abnormal expression.

miR-200 family could be regulated by some signaling pathways, for example, abnormal expression of AKT1 and AKT2 causes dysregulation of miR-200 family to regulate epithelial-mesenchymal transition (EMT) and CSCs self-renewal (Iliopoulos et al., 2009).

The present study provides novel basis for the abnormal expression of Tiam1 in CRC.