Sentence examples for for a thymus from inspiring English sources
Like the conventional NK (cNK) cells in the spleen, thymic NK cells are cytotoxic and require IL-15 but they differ from cNK cells by their characteristic expression of CD127 (IL-7 receptor α) and requirement for a thymus where they can arise from early thymocyte precursors (Vosshenrich et al., 2006; Ribeiro et al., 2010; Vargas et al., 2011).
We have previously demonstrated a requirement for the presence of a juvenile thymus for the induction of transplantation tolerance to renal allografts by a short-course of calcineurin inhibition in miniature swine.
Still, the results are "a good argument" for a rebirth of thymus function, says immunologist Brigitte Autran of the Pitié-Salpêtrière Pitié-Salpêtrière Hospitaleam uncovered some of the finst evidence that immune recovery might be Parisble.
The "T" stands for thymus, a small organ located between the lungs and behind the sternum where these cells mature.
The thymic index has been used as a surrogate for thymus volume, because it is strongly correlated (r ≥ 0.80) with the actual volume and weight of the thymus (Hasselbalch et al. 1996) (hereafter, the thymic index is referred to as thymus volume).
However, it does not support a role for the thymus in the pathophysiology of cGvHD, in contrast to the model discussed below.
In NaOAc/HOAc buffer at pH 3.29, this assay has a wide linear range for calf thymus DNA from 0.03 to 8.4 μg/ml with a detection limit of 10 ng/ml.
Phylodynamics of HIV-1 in lymphoid and non-lymphoid tissues reveals a central role for the thymus in emergence of CXCR4-using quasispecies.
The fluorescence intensity was measured using a SpectraMax M2 microplate reader (excitation and emission wavelengths were set at 355 nm and 460 nm respectively) and converted to DNA concentration by comparison to a standard curve for calf thymus DNA (Sigma-Aldrich) with concentrations ranging from 0 to 40 µg/ml.
Thus, the advance of gene therapy designing vectors specific for the thymus would be a major breakthrough in the thymus rejuvenation trials.
Collectively, our data establish that upregulation of a single transcription factor can substantially reverse age-related thymic involution, identifying FOXN1 as a specific target for improving thymus function and, thus, immune competence in patients.
