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Another possible explanation for the modest effect on BDI could be that the level of depression in the sample was too low (a mean BDI score at baseline of approximately 10) for a substantial effect to be expected from the intervention, though this explanation is not supported by a subgroup analysis of the data.
On the assumption that 2000 gait cycles per day would represent a clinically relevant difference with a standard deviation of 2000 gait cycles per day, power calculation showed that 27 patients would have to be recruited for a substantial effect (d = 1) to be observed with α = 0.008 (after Bonferroni correction) and β = 0.80.
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The study in the six European countries tested a variety of socio-demographic and illness-related variables as predictors for entering competitive employment but found a substantial effect only for previous work history [ 9].
Just a few heart attacks, for example, can have a substantial effect on the risk increase observed, as can the methodology used to analyze the data, some argued.
Because of these differences, influences and therapies for neuroplasticity must have a substantial effect size else large study populations are needed.
Changes in practices for diagnosing autism have had a substantial effect on autism caseloads, accounting for one-quarter of the observed increase in prevalence in California between 1992 and 2005.
However, the program is unlikely to have a substantial effect for three reasons: First, the program is very small; only about 30 women initially graduated from the course, and each is expected to work only a few days a month.
Restrictions on the services that can be provided for soft dollars could have a substantial effect on the money management industry and would most likely be opposed by many in that business.
For these policies to have a substantial effect, it is necessary to ensure technological and economic feasibility in the marketplace and to provide energy information that can be easily understood and evaluated by building owners and engineers.
For Norway, parental pressure had a substantial effect on the Overall reading factor on school level, while no such effect was found for Sweden.
Adjusting for casemix did not have a substantial effect on our findings.
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CEO of Professional Science Editing for Scientists @ prosciediting.com