Sentence examples for for a normal function from inspiring English sources

Next, we wanted to study whether it was possible to affect the Notch-associated differentiation of NB cells using HDAC inhibitors, since a functional Notch cascade relies on HDAC activity for a normal function of both RBP-J κ and Hes-1 (Grbavec and Stifani, 1996; Jimenez et al, 1997; Kao et al, 1998).

Thus, Ser172 residue in β tubulin appears important for a normal function of Dyn1p and Kar9p pathways at the mitotic stage in yeast cells.

For N gene, all the three conserved domains are indispensable for a normal function [ 29].

It has been shown that PKC-dependent phosphorylation at Ser801 is essential for a normal function of PC2 as an ER Ca2+ release channel [ 35].

This result is intermediate between Sod1−/− and control mice, suggesting a dose dependence of this effect and demonstrating that 50% SOD1 activity is not sufficient for a normal function of motor neurons in response to injury (Reaume et al., 1996).

They have found that reduced interhemispheric activity at rest is associated with motor deficits [Golestani et al., 2012], recovery of a normal interhemispheric coherence is important for a normal function, and motor impairments are not related to interhemispheric connectivity among attentional-related areas [ Carter et al., 2010].

ARHGAP24 is a gene necessary for a normal functioning Rho-pathway, which, as mentioned before, is an important regulator of the actin cytoskeleton [ 20].

These findings mirror what has been described from lamin A/C mutations, suggesting the importance of an intact nuclear lamina and LINC complex for a normal functioning heart (Ref. 78).

In summary, our finding that Aβ is an antimicrobial peptide is the first evidence that the species responsible for amyloidosis may have a normal function.

The pathophysiology of ELANE mutations in SCN is not completely understood, but evidence points towards a role for elastase in maintaining a normal function of the endoplasmic reticulum (ER) in myeloid precursor cells, leading to early apoptosis.

This is a normal function for these tubes, even tho they look gassy.