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PAGE A9 Alibi for a Microbe Pfiesteria piscicida, a marine microbe blamed for killing fish and endangering humans, may be innocent on both counts, some scientists say.
The deepest microbes that the researchers observed used just 0.001 femtomoles of oxygen per day; to put it another way, it would take 10 years for a microbe to consume the amount that a human inhales in a single breath.
Moviegoers might find fantasies like these entertaining, but for a microbe hunter like me, who spends his days trying to identify the viruses that cause dangerous diseases, the truth about the potential of global outbreaks is gripping enough.
That sounds clever for a microbe – how did they figure that out?
For a microbe, spread may be defined mathematically as the number of new victims infected per each original patient.
To date, obtaining a complete genome sequence remains one of the most efficient ways to gain insight into the biology of an organism, especially for a microbe whose biology may be difficult to study in its natural environment or in the laboratory.
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They are also highly specific; this is an advantage for detecting a microbe whose sequence is precisely known, but a great disadvantage for discovery of novel species, or for detecting variant strains of a known species.
They are also intolerant of primer-target mismatches; this is an advantage for detecting a microbe whose sequence is precisely known, but a great disadvantage for discovery of novel species, or for detecting variant strains of a known species.
It is found that a natural perspective for understanding a microbe is in terms of a hierarchy of variables at various levels of resolution.
For example, a microbe could be genetically engineered to detect a particular pathogen and kill it, for example, the bacteria Vibrio cholerae that causes cholera.
And the Federal Bureau of Investigation was struggling with a microbe for a murder weapon and a crime scene that stretched from New York to Florida.
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