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Isolated severe hypoglycemia at present appears the leading candidate for a mediating cause of the excess mortality, but other potential factors have not been excluded and current evidence is indirect and inconclusive.
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There is also evidence for a mediating role of ATP, acting on P2 purinoceptors.
However, none of those showed any suggestion for a mediating effect (data not shown).
A value of >1.96 (p <0.05) indicates support for a mediating effect [ 50].
Concomitantly, there is evidence for a mediating role of cAMP/PKA/CREB signalling in aspects of alcoholism modelled in animals.
However, it does not provide support for a mediating role of CVD risk factors in these associations.
Here, we review the neural circuitry in the brain for which there is currently the strongest evidence for a mediating role in placebo analgesia.
Evidence for a mediating effect of coping styles on the relationship between single motherhood and smoking was found for 'substance consumption'.
For a noble cause?
A fun night for a great cause!
Exercise for a good cause.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com