Sentence examples for for a given pathway from inspiring English sources
In panels A, B and D, vertical bars represent the magnitude of the psc for a given pathway.
For a given pathway, the proposed method estimates the log-likelihood ratio between different phenotypes based on the expression level of each member gene.
These methods can be divided into those based on summaries of results for individual expression probes (e.g., p-values) (FM, SM, KS, TS, MTS) and those based on joint modeling of all data for a given pathway (PCA, GMRE, GMFE).
The replication standard might be based upon the final model concordance and p values for a given pathway and outcome, rather than upon the findings for a pre-specified list of SNPs.
Figure 5 shows examples of models found by the GA in which the predicted values using an optimized model are plotted against the observed PC values for a given pathway.
When the kinase is present only at the membrane, the reaction-diffusion equation reduces to:
The ranking is done by obtaining GSEA p-values for enrichment of a given pathway P. We denote the highest-ranking l pathways based on p-value as { p1,…, p l } (the latter notation is unrelated to the numerical p values used here), these being the most differentially expressed pathways between the two classes.
This hole-filling is an iterative process, since introduction of new reactions into the network might justify the introduction of yet new pathways in the model, depending on the manually set cut-off for presence of a given pathway in the model.
For instance, pharmacological inhibition of a given pathway might be circumvented in a cell by epigenetic de-repression of a novel compensatory pathway.
Finally, pathway activity scores for each MetaCyc pathway were obtained by calculating the median hit count for reactions in a given pathway.
We summarize the coresponse statistics for all metabolites in a given pathway, p, to obtain a single statistic, b, that measures the coresponse between each transcript and that pathway in general.
