In this context we also point out that a PBN formulation can be used to exactly obtain the translation rate for a given initiation rate (without simulation), and so can be used more effectively in the iterative process, than simulation.
We also point out that the steady state translation rate and protein concentration can be solved from the first method by simulating the translation process for a given initiation rate, determining the translation rate, then determining the protein concentration and iterating.
We thus link the two processes and show that the import rate through a pore not only depends on the location of the initiation tag but also on the mechanical properties of the protein when averaged over all the possible geometries that are relevant for a given translocation initiation site.
The loss of cross-sectional area of steel is computed for a given corrosion initiation time in the next section.
Less than 50percentt of the recommended number of prenatal visits for a given gestational age and initiation of prenatal care after the first trimester is defined as "inadequate care" [ 18].
Given that the PSSR starts at a fixed LT, for a given longitude, and that the initiation point for the PSSR sweeps westward with the solar terminator, a tilt in isodensity contours should appear in the bottomside F layer with contours higher in the east.
For the 426 men who started bisphosphonates during follow-up, the estimated time of initiation for a given participant was the midpoint between the last known time point when he was a non-user and the first time point when bisphosphonate use was recorded.
The assessment of corrosion initiation risks also requires long-term and high-resolution climate simulated databases for a given location.
The above mechanisms not only help keep the cytoplasmic Ca2+ level at bay so that any increase from basal levels can be read as a signal of metabolic or environmental change, but also limit the free diffusion of Ca2+ so that the Ca2+ signals remain local, unless a given threshold for initiation of a propagating, global Ca2+ wave is breached (30).
As recently argued in a document of the European Society of Hypertension (5), this implies that rather than classifying drugs as 1st, 2nd, 3rd, and further choice, it might be more appropriate to help physicians select the drug (or drug combination) that might be preferred for treatment initiation in a given patient or a given clinical condition.
The discovery of a population of self renewing cancer stem cells in multiple types of cancer including lung cancer has led to the proposal that CSCs, not non-CSCs in a given tumor, are responsible for tumor initiation and possibly metastasis [12], [13], [24].
