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A 3-D finite element model is built for a further validation.
For a further validation, we exposed murine fibroblastic L-cells transfected with TOPflash to oscillatory fluid flow.
Among the differentially expressed miRNAs, we chose hsa-miR-363* for a further validation study because its upregulation in centenarians was detectable by qRT-PCR analysis with > 2 fold change.
Indeed, to focus on genes for which differential methylation and expression could be related, we applied larger sample cohorts (78 paired HCC samples) for a further validation using Illumina MiSeq-BSP (Fig. 2).
Furthermore, recently developed high-throughput protein biomarker screening methods, such as multiple reaction monitoring, could be applied to a broader cohort of samples for a further validation of the observed biological changes (Sandhu et al. 2008; Whiteaker et al. 2007).
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For this, a further validation of radius quantification was carried out against a partially rescanned portion of the network at 8 μm voxel size, which estimated less than 10% radius error in vessels larger than 2 voxels in radius.
For the sake of completeness, a further validation of this approach is here reported, based on simulations about propagation.
We have experimentally validated a large number of Perlegen-generated CNV calls with the independent method qPCR and demonstrated their inheritance through families as a further validation for the CNV calling [9].
A further validation used for the description is the prediction of caloric parameters and the comparison thereof with measured data.
This work can serve as an example workflow for potential users as well as a further validation data set.
A consistency assessment of the results across datasets is fundamental in verifying their reliability and in deciding for a further biological validation step [ 56].
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for a reliable validation
for a full validation
for a preliminary validation
for a visual validation
for a separate validation
for a first validation
for a worldwide validation
for a free validation
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for a qualitative validation
for a clinical validation
for a complete validation
for a statistical validation
for a comparative validation
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for a global validation
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