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The main limitation of this study was the potential for a confounding bias due to its observational design.
Paper organization - I would suggest introducing the current work as an attempt to account for a confounding factor so far overlooked.
The final model was diagnosed for goodness-of-fit using Hosmer-Lemeshow test [ 24] in LDdiag [ 49] in R. Confounding was tested monitoring the change of logit of factors by removing a suspected factor from the model [ 20], and association between the factors suspected for a confounding was tested where necessary.
A third program DESIGNM was written to compute such a formula (from [ 1], p.294), but DESIGNM does not adjust for a confounding variable, and that strong assumption of implicit matching is rarely justified in case-control studies, so this program was not made freely available.
16 It is important to emphasize that there are three criteria for a confounding factor: a confounder must be associated with the disease (either as a cause or as a proxy for a cause but not as an effect of the disease); a confounder must be associated with the exposure; and a confounder must not be an effect of the exposure.
Sexuality is a simple word for a confounding landscape of feelings, sensations and thoughts: excitement, confusion, comfort, longing, disappointment, fear, rejection.
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All analyses adjusted for a-priori confounding factors, age, sex, rank and engagement status [ 11, 18].
These variables, therefore, did not meet the requirement of a confounding variable for our purposes.
Multiple Cox regression analysis was used to analyze association and to adjust for age as a confounding factor, at a rejection level of 5%%.
Partial correlations were computed to control for age as a confounding factor.
This strategy was used to control for a possible confounding effect between depression and DASs.
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