At the same time, the sampling time for HT1080 cells has a broad interval and fluorescence of the treated cells can be measured even after 5 7 days without a significant effect on the calculated rate of HAC loss (see Additional file 1).
Furthermore, whereas Malinen et al. [ 15] used a relatively broad interval for the higher frequencies (0.12 – 0.25 Hz), we were able to show that the upper end of the high-frequency interval (between 0.20 and 0.24 Hz), in particular, might be relevant in chronic pain disorder.
The Ehrlichia group shows a very broad interval range for the "maximum" likelihood value and the lower boundary of α value is 0.39 (Table 4).
Therefore, the roughness can be changed in a very broad interval by changing the deposition parameters.
Second, the time between evaluations was not rigidly fixed; however, rather than being a drawback, this allowed for a broad range of follow-up intervals and the ability to separately view data according to duration of follow-up category.
However, the design of this study has been criticised, mainly for failure to measure oxidative stress and vitamin E levels in most of the patients [ 16- 18] and because the study had a small sample size with resultant wide confidence intervals for a broad composite endpoint [ 19, 20].
Understanding the mechanisms that dictate protein stability is of large relevance, for instance, to enable design of temperature-tolerant enzymes with high enzymatic activity over a broad temperature interval.
It shows a broad melting interval at 70°C besides a glass transition at −30°C.
Positive LOD scores extended over the entire region, continuing to define a broad candidate interval.
For a threshold of 7.20, the odds ratio was lower (4.3, 2.2 to 8.7), with a broad predictive interval (0.5-40.6).
