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We found two major types of changes in the footprint pattern of fore- and hindpaw of aged animals.
Polymerase binding protects DNA from cleavage resulting in a well-established footprint pattern consistent with previously published rrnB P1 footprints [34].
The addition of higher amounts of Rsd reduces the intensity of the footprint pattern, resulting in almost a total disappearance of the footprint and also the retardation pattern at the highest Rsd concentrations (Figure 2a and b, lanes 8 13).
Interestingly, we observed significant changes in the footprint pattern upon the addition of Pol II (lane 5).
The footprint test is a common qualitative readout that displays the footprint pattern and footprint contacts, potentially highlighting gait abnormalities [ 13].
MouseWalker can generate such a readout displaying the footprint pattern generated by the walking animal in addition to the path created by the body center (Fig. 3a).
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Furthermore, we analyzed footprint patterns as previously described18 at ~50 days post-rAAV delivery.
What places can accurately claim to be "steps" from 1600 Pennsylvania Ave . Transform the adjoining crosswalks into footprint patterns.
The typical footprint patterns of control KO, treated KO and WT mice are shown in Fig. S2B.
But so sanitized was the "Pastel Punk" from the House of Holland, with its soft colored plaids, polite mesh tops, footprint patterns and sweet smiles from the models that wild defiance on the runway seemed far away.
These studies have used a variety of measurement techniques, to include ground level photography and in situ measurements, aerial photography, satellite imagery and vehicle-mounted global positioning systems (GPS) data to define the footprint, patterns and magnitude of disturbances on the landscape.
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