Sentence examples for footprint extension from inspiring English sources

In this work, we analyzed ribosome profiling data obtained for Escherichia coli and Bacillus subtilis and have shown that the length and distribution of ribosome footprints at SD site-containing mRNA regions is consistent with 'the caterpillar model' of progressive footprint extension.

To investigate directionality of footprint extensions, we analyzed aggregated density of both 3′ and 5′ footprint ends relative to SD site position for the footprints of individual lengths.

However, as we demonstrate here, the footprint extensions are sequence dependent and are not equivalent at the 5′- and 3′-ends.

First, to distribute the pause over three adjacent codons, the probability of P-site codon locations were set at P x = P x + 3 = P x + 6 = 3 P. Second, to model asymmetric extension, footprint lengths were extended at their 5′-end for P-site codon locations at x + 1 to x + 6 by the distance between the P-site and x. 'The caterpillar model' of SD-mediated footprint elongation is shown in Figure 1B.

To model SD site-dependent extension of footprint lengths, footprints were generated under a similar model with two alterations.

They also want people who are increasing their carbon footprint by building extensions to have to make efficiency improvements to the existing structure.

We find that the release scores for C-terminal extensions fall well within the distribution for those of annotated coding regions, which again supports the notion that the ribosome footprint density covering extensions represents bona fide translation events, followed by termination at the expected stop codon.

Addition of RNA polymerase led to an extension of the footprint to +14 and produced a new footprint from −61 to −59 upstream of the Mor-binding site (Artsimovitch et al. 1996; Ma and Howe 2004).

(E ) Ratios of the ribosome footprint density in putative extensions to corresponding coding regions.

Thus, footprints aligning to extensions appear to be protected by 80S ribosomes.

Chromatin was subjected to MNase or DNaseI digestion for the low-resolution indirect end-labeling (IEL) analysis or primer-extension footprinting, respectively, as described earlier [ 14].