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The maturation experiment was performed with the following maturation pre-treatments: normal tap water, a 21.25 kg m−3 brine solution and without maturation.
The MVC force, averaged across all directions and normalized to the adult values, exhibits the following maturation curve: %MVC Force=−0.0879 age)2+8.120(age)+8.120.
The rate of endocytosis is known to slow following maturation of DCs [2]; and, consistent with this, we observed a dramatically (10-fold) reduced rate of quantum dot uptake in DCs matured by treatment with LPS (Figure 2N).
These results indicate that the forebrain progenitors derived from hiPSC, similar to those from hESC, can further differentiate into forebrain glutamatergic neurons following maturation from NE cells to dorsal telencephalic cells in absence of known morphogens.
Since Bcl-2 is a prominent survival factor that has been implicated in preventing programmed cell death in T cells, and is required for prolonged lymphocyte survival following maturation [35], we examined the expression of Bcl-2 in thymocytes from OT-II and OT-II/Itk−/− mice.
4) The authors need to provide more background information/rationale regarding why they looked at ZP2 conversion following maturation.
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Further evidence of maturation following growth factor treatment in cartilage explants are an increase in the ratio of mature to immature collagen crosslinking and developmentally encoded changes in extracellular distribution of proteins such as perlecan.
Remnants of the seed remain attached to the seedling during almost the entire early development, and first disappear following the maturation of the first fully differentiated ("true") leaves (stage IV).
This is the first report to describe an α-helix as a principal component of a naturally derived VH CDR3 following affinity maturation.
To determine a potential role for MeCP2 in neuronal chromatin maturational changes, we measured nucleoli and chromocenters in developing wild-type and Mecp2-deficient mouse cortical sections, as well as mouse primary cortical neurons and a human neuronal cell line following induced maturation.
Murine immature DC were shown to induce Treg suppressive activity in vitro whereas following DC maturation induced by TLR ligation, Treg suppressive activity was inhibited [48].
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