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The entire tumour section was assessed and analysis was carried out on a quantitative basis with the following grading applying throughout: −: no staining; positive staining was scored follows: + : </= 5% of tumour cells positive; ++ : >5 25%; +++ : 25 50%; ++++ : >50 75%; +++++ : >75 100%.
For staining intensity the following grading was used (relative to the strongest staining observed in the specific renal compartment of interest): 0 = no staining, 1 = weak staining, 2 = moderate staining, 3 = strong staining, 4 = most intense staining observed.
The following grading system was used to quantify vascular changes as observed on angiography: Grade 0, normal retinal vasculature; +1 point for each of the following changes: dilated or tortuous vessels, microaneurysmal-like hyperfluorescent dots <10 or hyperfluorescence around the optic nerve head; +2 points for microaneurysmal-like hyperfluorescent dots >10.
Mean maximum severity scores for EAE were done using the following grading criteria: Grade 1. limp tail; grade 2. limp tail and weak hind limbs; Grade 3. hind limb paralysis; Grade 4. fore limb paralysis; Grade 5. moribund; Grade 6. death.
For surface area stained the following grading system was used (relative to the total area of the specific renal compartment of interest): 0 = no staining, 1 = 0 25% area positive, 2 = 26 50% area positive, 3 = 51 75% area positive, 4 = 76 100% area positive.
The histopathological changes were scored using the following grading system: 0 = none, 1 = minimal, 2 = slight, 3 = moderate, and 4 = marked lesion.
Similar(38)
The inclusion of items pertaining to the preceding and following grades was used to confirm the difficulty of each item.
A previous meta-analysis by Philips et al. [6] ultimately advised against surgical treatment following grade III acromioclavicular separation.
They suggested that the rationale of surgical reconstruction to achieve anatomic alignment for full functional recovery may not always be achieved following grade III acromioclavicular separation [8].
The purpose of this study was to compare the clinical outcomes of patients managed operatively and non-operatively following grade III acromioclavicular dislocation.
The authors were asked to write texts that would be a complete and coherent text and also be part of the text presented in the following grade.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com