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A more likely explanation for the performance gap between predictive models for embryonic stem versus differentiated cells is the increasing heterogeneity in regulatory mechanisms following differentiation.
Moreover, PINK1 expression was found to increase up to ∼100 fold following differentiation to neurons, (Figure 1C) suggesting a physiological role of PINK1 within differentiated human neurons.
At later stages, younger beta-cells join the islet following differentiation from post-embryonic progenitors.
However, how pathogenic T-effector cells are regulated following differentiation, which represents the T-cells in the inflamed lesions, is relatively unclear.
On account of (12), we derive the following differentiation result.
Based on the gH-difference, Stefanini [21] proposed the following differentiation.
From [3] we recall also the following differentiation formula, expressed in a modified way, which will be helpful.
To suppress these noisy components generally a smoothing operation is employed as the post-processing step following differentiation.
Ex vivo studies were designed to investigate effects on HIV-1 infection in macrophages exposed to THC during or following differentiation.
A clonal population was isolated with this deletion and following differentiation we confirmed loss of exon 51 from the dystrophin mRNA transcript and restoration of dystrophin protein expression.
Thus, the implantation of a basic TEC lead to the in vivo differentiation of such TEC in response to the in vivo biological and biomechanical cues following differentiation.
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