Theoretically, OPG could reflect one or more of the following: atherosclerotic burden, myocardial ischaemia, arrhythmia risk or the degree of ventricular dysfunction.
Criteria for selecting the health status instrument to be used in the questionnaire included the following: low burden to respondent and data collector; conceptual appropriateness; ease of translation and cultural adaptation; and established psychometric properties.
Accordingly, Pennock et al. 4 describe four patterns of response for ipilimumab (Yervoy): response in baseline lesions, gradual decline in tumor burden, response following increase in tumor burden, and response in index lesion with new lesions that subsequently regressed.
6 The UK Burden of Injury Study also estimated considerable burden following injury for people seen in ED but not hospitalised, partly due to the greater numbers with injuries not resulting in hospitalisation.
One commentator has said that the applicant's task is to discharge his or her evidential burden, following which the public authority detaining the applicant has a legal burden of showing that the detention is lawful.
In order to determine the effect of parecoxib on nitrosative burden following I/R, hepatic tissue levels of iNOS and nitrotyrosine were evaulated.
The search strategy utilised a combination of the following search terms: 'Burden of disease and injury in Aboriginal and Torres Strait Islander Peoples'; [OR] 'Burden of disease' AND 'Aborigin*'.
It is likely, therefore, that many of the socioenvironmental determinants of psychosis, as well as the societal burden following onset, are placed upon our poorest communities, who in effect become doubly disadvantaged.
However, blocking the OPG/RANK/RANKL pathway with RANK-Fc had no effect on tumor cells in nonosseous sites; the decrease in tumor burden following inhibition of the tumor-mediated osteolysis is an indirect effect secondary to interruption of the vicious cycle of osteolytic metastasis [ 43- 45].
All parts were translated into Kannada following Lifting The Burden's translation protocol [14].
