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Liver glycogen content increased at 12 months, followed by a significant decrease at 16 months.
This rise in nestin expression was transient, as it was followed by a significant decrease at 48 hours.
Their expression was relatively high at two weeks after pollination (WAP) and remained high at 5 WAP, followed by a significant decrease at 6 WAP (Fig. 4a).
In BaP-treated animals, a significant increase in hepatocyte lipid contents was observed from 6 to 18 hours post-exposure followed by a significant decrease at 24 hours.
The fluorescence intensity per ICG then decreases at 300 1 and 350 1, followed by a significant decrease at 500 1.
Both blood and urinary cadmium levels and also smoking were associated with micronuclei in an unexpected way, with an initial (non-significant) increase in micronuclei, followed by a significant decrease at higher cadmium levels or higher levels of smoking.
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There was a significant up-regulation from 6 hpi to12 hpi with expression peaking at 2.6, followed by a significant decrease to 0.9 at 24 hpi and remained unchanged at 48 hpi as opposed to 12 hpi.
Interestingly, CD62L expression peaked at day 6, followed by a significant decrease in expression at day 8 (data not shown).
This level remained unchanged until 9 wpi followed by a significant decrease to +0.5 at 10 wpi.
Since the mice were sacrificed after 5 hours of HVT-ventilation, we could not evaluate whether the downregulation in mRNA expression was followed by a significant decrease in protein expression at a later time point.
On the other hand, the exenatide meal tolerance test was followed by a significant decrease in plasma glucose, with a trough at 2 h after the test (p < 0.001).
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