Exact(1)
Upon ligand binding, GPCRs undergo activation followed by a decrease in receptor responsiveness (desensitization).
Similar(59)
AML cell number in peripheral blood was rapidly declining after chemotherapy and partly followed by a decrease in lymphocytes, not sufficient to explain the increase in T-cell receptor related genes.
In the present experiments inhibition of CGRP receptors prevented the increase in spinal trigeminal activity induced by infusion of nitroglycerin, later followed by a decrease in activity below baseline.
That is, a relatively high, early rate of diversification followed by a decrease in speciation rate.
TLR3, a toll-like receptor eliciting an antiviral response in the presence of HPV oncogene expression, is increased in CIN3 followed by a decrease in CxCa [ 24].
They noted a strong p21 induction, a decrease in Rb phosphorylation followed by a decrease in total Rb level.
This leukopaenia is followed by a decrease in megakaryocytes and finally in the erythropoietic series.
Castration of tumour-bearing hosts induced tumour growth arrest, followed by a decrease in tumour size.
This peak expression was generally followed by a decrease in transcript abundance.
Again, the expression peak was generally followed by a decrease in transcript accumulation.
Accordingly, our results demonstrate that the ACh or CCh induced shift of the cell phenotype towards a proliferative one, was followed by a decrease of the M3 receptors density, as shown by decreased [H]NMS binding in cells incubated with ACh or CCh for 7-15 days.
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