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Many of the drugs examined in these studies were shown to be ineffective in follow-up proof-of-principle studies.
Therefore, significant follow-up validation is required of findings resulting from HAM analysis in order to provide the absolute proof of the validity of the genotype/phenotype relationship.
As we did not routinely do resections and do not yet have 10-year follow-up, the proof of excluding ACT/CS1 in the three unsuspicious larger lesions was incomplete.
Group 2 comprised 65 lesions in which the diagnosis was made by the combination of clinical findings and/or follow-up without histopathological proof as the gold standard.
11 As a follow-up to this proof-of-concept study, we next turned our attention toward translating this concept to a post-SAH conditioning paradigm.
Similarly, as seen in the IALT discussed above, in CALGB 9633 the benefit of adjuvant faded with time and emphasised the need for prolonged follow-up to establish the proof of benefit in adjuvant setting.
Follow-up alone was the proof of diagnosis in 4 patients for the primary site, in 14 patients for lymph node status, and in 28 patients for the remainder of the body, respectively.
The follow-up to 2001's Living Proof features a tantalising list of collaborators, rumoured to include Jake Shears, Timbaland, Lady Gaga and Pink.
It got a rare two-series commission late last year, and the change of transmission – from releasing the series in bulk on iPlayer to putting out weekly episodes with a follow-up showing on BBC2 – is proof that the Beeb believe PJDN is becoming about as close to appointment-TV as it's possible to get in the Netflix age.
Titled "Closer to the Truth," the disc is Cher's long-awaited follow-up to 2001's "Living Proof," which included the dance hit "(This Is) A Song for the Lonely".
This paper presents the results of high-energy TWDEC simulation experiments as a follow-up to the previously reported proof-of-principle experiments for low energy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com