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Furthermore, similar longitudinal follow-up methodology which should maximize the diagnosis rate was also employed in a study of German cohort where a relatively distinct trend towards an association was found (OR = 2.47, P = 0.11) [8].
Follow-up methodology has been reported [ 11].
20 The methods for this registry have also been described elsewhere, and the VSTR and VOTOR share a common follow-up methodology.
Furthermore, they raise questions regarding follow-up methodology in terms of nurse-led follow-up clinics, perhaps for those patients at low risk for recurrence, and more focused medical follow-up of those at high risk for recurrence.
Whilst there were higher response rates to the EQ-5D and NDI as opposed to the SF-12 this can be explained, at least in part, by the follow-up methodology within MINT (missing EQ-5D and NDI questionnaires were chased by postal reminders and telephone contacts, whilst missing SF-12 questionnaires were chased by postal reminders only).
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It must be stated that follow up methodology varied among the participating centers, and it is not clear if it was masked.
One should consider the difficulty of compliance with a face-to-face annual follow-up study methodology in a highly mobile age group (moving to a high school or going to a university in a different city, starting paid work, or going to military service after high school).
Standard Operating Procedures (SOP) detailing follow-up survey methodology for each examination station were prepared and read by all study team members.
As can be appreciated, type of surgery, duration of follow-up, and methodology vary enough to preclude precise quantitation of the impact of weight loss on insulin sensitivity.
There was a difference of 1.9 months in median duration of follow-up (reverse Kaplan Meier methodology) between regions (EU, 13.7 months; NA, 15.6 months), with no significant differences between study arms within each region.
After several years, or even decades, of posttherapeutic follow-up by distinct methodologies, several studies have revealed important contradictions amongst PCR and serological results (conventional and nonconventional).
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