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In the patients who underwent rigorous follow-up detection of SPC was assured.
From all including studies were obtained: first author' surname, publication year, sample size of cases and controls, treatment, duration of follow-up, detection rate.
The follow-up programme was based on the guidelines of the Dutch Association of Comprehensive Cancer Centers of the nineties (Vademecum Oncologie, 1992), which is merely based on expert opinion than on evidence on how often patients should be reviewed to fulfill the goals of follow-up (detection of recurrence, detection of side effects of treatment, and psychosocial support).
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These two problems make follow-up defect detection difficult.
Patients underwent follow-up for detection of HCMV viremia or disease (groups A and B) and for discontinuation of HCMV secondary prophylaxis on the basis of either HCMV-specific or absolute CD4+ T cell count (group C).
Follow-up for detection of recanalisation after 6 months may not be necessary [36].
Close follow-up, early detection and aggressive treatment of second malignant neoplasms can improve the outcome.
We excluded malignancies diagnosed during the first year of follow-up avoiding detection of indolent tumours by increased surveillance.
Altogether this indicates that children with CCSK need extended and more intensive follow-up for detection of relapses than, for instance, patients with nephroblastoma.
An emphasis on psychological impact in the postoperative follow-up and detection of possible psychological needs or need of support throughout the treatment course are important [ 14].
Imaging in a cancer patient is typically performed for diagnosis, staging, treatment planning, response evaluation, follow-up and detection of recurrent disease.
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