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Exclusions include women whose registry based follow up has ceased due to reported hysterectomy, gynaecological cancer, or migration, or those whose most recent Pap test showed a high-grade abnormality (these women require a different follow up pathway).
Follow up pathway and functional analysis using Ingenuity Pathway Analysis® (IPA) tools, a web based interface for Ingenuity Knowledge Base (Ingenuity® Systems, http://www.ingenuity.com) shows several pathways over- or under-represented in the active site nsSNV dataset, with the most significantly affected pathways involved in carbohydrate metabolism.
As a follow up to our regression models, we examined pathways of mediation (Fig. 1).
Three pieces of advice: follow up, follow up, follow up.
Follow up, follow up and follow up.
Follow Up.
Follow up, follow up, follow up.
Follow up.
Follow up promising contacts.
Currently, risk stratification in relation to cancer tends to focus on risk of recurrence and is used to inform follow-up pathways.
While the developmental surveillance program rolled out in NSW using PEDS and ASQ is an excellent example of how early identification and follow-up pathways might operate, the uptake of the program appears to be variable, possibly due to a range of factors including several barriers facing families, training limitations for professionals, and resource constraints for health services.
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