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"This may help explain why alcoholism is such a powerful addiction, and may one day contribute to new ways to treat alcoholism or help prevent at-risk people from becoming addicted". More research will surely follow to replicate these results and evaluate potential changes to other genes as well.
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Descriptions in the Clemens family archives have been followed to replicate as nearly possible the decorations in the dining room, and the cake and party favors to be distributed today in the carriage house.
A larger representative sample and longer-term follow up are needed to replicate the current present findings.
We acknowledge that the few significant associations found in our analysis may be attributable to chance alone, and larger follow-up studies to replicate the findings are warranted.
This followed the perceived need to replicate and recover large quantities of durable heartwood.
Few, if any, of the architects who followed Mies were able to replicate the subtlety of such works.
The apparent cure of the "London patient," who has not been identified, follows several unsuccessful efforts to replicate the 2008 experience of Timothy Brown, the "Berlin patient" who underwent treatment for leukemia and gained a robust resistance to HIV in the process.
To determine the effect of the SNPs near TCL1A on estrogen withdrawal and on NF-κB transcriptional activity, we treated Human Variation Panel LCLs - three with WT SNP genotypes and three with variant SNP genotypes, all stably transfected with ERα - with low concentrations of estrogen, followed by ER blockade to replicate the estrogen withdrawal that occurs during AI therapy.
In fact, the confirmed five loci were the first ones to be published whereas the SNPs on 14q22.2, 16q22.1, 19q13.1 and 20p12.3 were only captured by meta-analysis of large GWAS (Houlston et al, 2008), suggesting that these four could be more difficult to replicate in follow-up studies.
"This center is a great example for other regions to follow and replicate," he said.
In one of the most poignant moments in her book, Harrington visits a group of women in a follow-up study designed to replicate Spiegel's stunning data.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com