Sentence examples for folding principles from inspiring English sources

Furthermore, we show how physical constraints, such as nuclear size, correlate with the folding principles of chromatin.

Previous studies indicated that disruptive amphipathicity formed by replacing the paired charged amino acid residues on the polar face of an amphipathic helix with tryptophan residues linked with hydrogen bonds on the basis of α-helical protein folding principles endowed the AMPs with increased cell selectivity.

Anginex, a novel artificial cytokine-like peptide (βpep-25), is designed by using basic folding principles and incorporating short sequences from the β-sheet domains of anti-angiogenic agents, including platelet factor-4 (PF4), interleukin-8 (IL-8), and bactericidal-permeability increasing protein 1 (BP1).

Owing to their folding principles, structural diversity, secondary structure stability, and resistance to proteolysis, β-peptides represent a promising class of compounds to elucidate mechanisms of AMP activity and to template development of new antifungal therapeutics.

In the study, Lieberman-Aiden et al. modeled the Hi-C data as a probability matrix at a large scale (1 Mb resolution) and revealed the folding principles of genome organization with a sub-domain of chromatin to form genome-wide compartments.

Lieberman-Aiden, E. et al. Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome.

The secondary structures of pre-miRNAs were generated using the Mfold 3.2 software, which is based on Zuker folding algorithm principles [ 48].

In principle, folding nucleus symmetric expansion can be applied to any given symmetric protein fold (that is, nearly one-third of the known proteome) provided information of the folding nucleus is available.

If this correlation were not observed, then in principle the folding free energy of proteins could (on average) be more stabilising at an alternate pH.

A folding ruler based on similar principles has been reported.

And since the rates of direct and reverse reactions are equal at the equilibrium point (as follows from the physical "detailed balance" principle), the estimated folding time can be derived from the estimated unfolding time.