Sentence examples for folding alterations from inspiring English sources

The RMSD values of the native and mutant structures were significantly similar for both RpoS and TviE, suggesting similar levels of protein folding alterations.

This result was somewhat expected, given that dye fluorescence is not affected by folding alterations or enzymatic degradation.

Single base modifications can result in folding alterations and functional loss.

To date, it has been difficult to distinguish whether the observations arise from substitutions causing structural or folding alterations in parkin or are a result of disrupted protein interactions with E2 ubiquitin conjugating enzymes, potential substrates, or the S5a proteasomal subunit.

UPR is a cellular response to protein folding alteration orchestrated by different effectors that may lead either to cell survival or to cell death depending on the strength and duration of the stimulus.

The vibrational spectrum of SCN and other environmentally sensitive vibrational probes can yield quantitative information on the changes in the local electric field around the probes upon ligand binding, protein folding, alteration of the surrounding hydration shell, and protein protein association.

At large molecular sizes the distribution shapes become less sensitive to the relatively small sized chemical modifications, or proportionally subtle conformational changes as compared to major fold alterations.

8, 9 The UPR is a series of complementary adaptive mechanisms to cope with protein-folding alterations.

Genes showing >2-fold alterations in expression between the MCF-7/S0.5 and TAMR cell lines were selected as input data in the first analysis.

This shows that the majority of significant differentially expressed genes show only small to moderate (up to 2-fold) alterations in gene expression.

In addition, an enrichment analysis using gene set enrichment analysis [ 36] to identify over-represented pathways and genes was performed on genes exhibiting >2-fold alterations in expression between MCF-7/S0.5 and TAMR cell lines.